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Innovation research themes

Diagnostics & Biomarkers

Transforming healthcare with innovative diagnostics

We’re working to improve diagnostic devices for diabetes, immune-related bowel disease, cancer, and genomics. By building the right systems and infrastructure, we aim to ensure these tests are accurate, effective, and affordable—helping patients to get the right care faster. Our research focuses on both lab-based and real-world diagnostics to improve health outcomes and make a real difference to people’s lives.

The critical role of diagnostics in healthcare

Diagnostics are essential in the NHS, helping doctors detect diseases, predict outcomes, and tailor treatments for personalised care. While new diagnostic technologies offer great potential, proving their effectiveness, safety, and impact is complex, slowing their implementation. Expertise, collaboration and high-quality evidence are key to ensuring new tests reach patients quickly and effectively.

Leaders in diagnostic innovation and patient involvement

We’re at the forefront of developing, evaluating, and implementing cutting-edge diagnostics for conditions like diabetes, dementia, cancer, and immune-related diseases. Our work bridges the gap between research and real-world application, ensuring new technologies meet NHS and regulatory standards. 

People are at the heart of our research. By working with the Exeter Clinical Trials Unit we involve people in research that could directly benefit them. We also collaborate with major diagnostic manufacturers, leading universities, and hospitals to expand our research and clinical testing.

Collaborating for better health outcomes

Partnerships are key to driving innovation in diagnostics. We collaborate with major partners to develop diagnostic tools for diabetes, Crohn’s disease, and cancer, bringing together experts across disciplines to accelerate the assessment and adoption of cutting-edge diagnostics. We also work with charities, patient groups and healthcare partners to evaluate new diagnostics, improving patient care and healthcare through a dedicated pipeline.

Theme Leads

Professor Tim McDonald

Professor Timothy McDonald

Theme Lead, Diagnostics & Biomarkers
“There are a lot of exciting diagnostics coming out which could improve diagnosis and NHS services, helping patients to get the treatments they need as quickly as possible. But we want to ensure that only effective tests and treatments reach the market and patients – we aim to be a one stop shop for companies and researchers to assess their diagnostic innovations, providing the scrutiny necessary to make sure they’re safe.”

Professor Nick Stone

Co-Theme Lead, Diagnostics & Biomarkers
“Being part of the HRC allows us to take a holistic approach to HealthTech innovation. By combining expertise across every stage—from clinical and safety evaluation to economic assessment—we create safer, more effective technologies that benefit patients and NHS services regionally, nationally and beyond.”

Diagnostics & Biomarkers projects and case studies

Scientist dropping a sample into a Petri dish
Project

GenomeKey: Novel blood diagnostic for rapid bacterial pathogen identification and AMR

Two medical blood test tubes in hand of medical laboratory assistant
Project

CanSense-CRC early detection novel blood test for bowel cancer (Raman spectroscopy and machine learning)

Nurse carrying out a diabetes test.
Case Study

Type 1 Diabetes Genetic Risk Score (T1D-GRS)

Lady using a mobile phone

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